講者:吳錫金
日期:2016-05-10
觀看: 1517
  • 00:00 1.
    Novel Therapies for Patients with Metastatic Prostate Cancer Part 1Cabazitaxel (Jevtana,去癌達)
  • 00:07 2.
    Outline
  • 00:46 3.
    In 2004 docetaxel &predsisone was established as the new standard of care for patients that progressed on ADT
  • 02:23 4.
    Cabazitaxel (JEVTANA®): a next-generation taxane
  • 03:16 5.
    Mode of action of Cabazitaxel
  • 04:03 6.
    Cabazitaxel Preclinical Summary
  • 04:41 7.
    Cabazitaxel in Second-line CRPCTROPIC Phase III Study
  • 05:35 8.
    Primary Endpoint: Overall Survival Cabazitaxel prolong survival vs. mitoxantrone in p’t progressed on docetaxel
  • 06:07 9.
    Secondary Endpoint:Cabazitaxel Significantly Improved PFS
  • 06:19 10.
    Secondary Endpoints:Cabazitaxel Significantly Improved Tumor and PSA Endpoints
  • 06:41 11.
    Cabazitaxel : Subgroup Analysis of Overall Survival
  • 07:26 12.
    Patients with initial PSA flare during cabazitaxel therapy are good responders
  • 08:14 13.
    Severe neutropenia during cabazitaxel treatment is associated with survival benefit in men with mCRPC: A post-hoc analysis of the TROPIC trial
  • 09:14 14.
    Cabazitaxel: Main Adverse Events
  • 09:49 15.
    Management of Select Adverse Events
  • 09:50 16.
    Cabazitaxel Premedication
  • 10:04 17.
    Management of Neutropenia*
  • 10:17 18.
    Growth Factor Support
  • 10:47 19.
    Comparison of Adverse Events TROPIC vs CUP/EAP
  • 11:08 20.
    Slide 20
  • 11:25 21.
    Slide 21
  • 11:40 22.
    Slide 22
  • 11:48 23.
    Cabazitaxel remains active in patients progressing after docetaxel followed by abiraterone
  • 12:13 24.
    Efficacy of Cabazitaxel in CRPC is independent of the presence of AR-V7 in circulating tumor cells
  • 12:30 25.
    Slide 25
  • 12:32 26.
    Characteristics of phase III trials examining upfront docetaxel chemotherapy for mHSPC
  • 12:48 27.
    Current Clinical Trials with docetaxel or Cabazitaxel
  • 12:51 28.
    Treatment Landscape
  • 索引
  • 筆記
  • 全螢幕
【醫藥護人員場】3. Novel Therapies for Patients with Metastatic Prostate Cancer
長度: 13:41, 瀏覽: 1518, 最近修訂: 2017-05-09
演講時間:9:10-10:10
講者:吳錫金院長
現任職位/稱:
中國附醫北港分院院長
亞洲大學健康暨管理學院健管所碩士
泌尿科醫學會泌尿腫瘤委員會委員 
 
 
    • 00:00 1.
      Novel Therapies for Patients with Metastatic Prostate Cancer Part 1Cabazitaxel (Jevtana,去癌達)
    • 00:07 2.
      Outline
    • 00:46 3.
      In 2004 docetaxel &predsisone was established as the new standard of care for patients that progressed on ADT
    • 02:23 4.
      Cabazitaxel (JEVTANA®): a next-generation taxane
    • 03:16 5.
      Mode of action of Cabazitaxel
    • 04:03 6.
      Cabazitaxel Preclinical Summary
    • 04:41 7.
      Cabazitaxel in Second-line CRPCTROPIC Phase III Study
    • 05:35 8.
      Primary Endpoint: Overall Survival Cabazitaxel prolong survival vs. mitoxantrone in p’t progressed on docetaxel
    • 06:07 9.
      Secondary Endpoint:Cabazitaxel Significantly Improved PFS
    • 06:19 10.
      Secondary Endpoints:Cabazitaxel Significantly Improved Tumor and PSA Endpoints
    • 06:41 11.
      Cabazitaxel : Subgroup Analysis of Overall Survival
    • 07:26 12.
      Patients with initial PSA flare during cabazitaxel therapy are good responders
    • 08:14 13.
      Severe neutropenia during cabazitaxel treatment is associated with survival benefit in men with mCRPC: A post-hoc analysis of the TROPIC trial
    • 09:14 14.
      Cabazitaxel: Main Adverse Events
    • 09:49 15.
      Management of Select Adverse Events
    • 09:50 16.
      Cabazitaxel Premedication
    • 10:04 17.
      Management of Neutropenia*
    • 10:17 18.
      Growth Factor Support
    • 10:47 19.
      Comparison of Adverse Events TROPIC vs CUP/EAP
    • 11:08 20.
      Slide 20
    • 11:25 21.
      Slide 21
    • 11:40 22.
      Slide 22
    • 11:48 23.
      Cabazitaxel remains active in patients progressing after docetaxel followed by abiraterone
    • 12:13 24.
      Efficacy of Cabazitaxel in CRPC is independent of the presence of AR-V7 in circulating tumor cells
    • 12:30 25.
      Slide 25
    • 12:32 26.
      Characteristics of phase III trials examining upfront docetaxel chemotherapy for mHSPC
    • 12:48 27.
      Current Clinical Trials with docetaxel or Cabazitaxel
    • 12:51 28.
      Treatment Landscape
    位置
    資料夾名稱
    2016臺大攝護祭-醫藥護人員場
    發表人
    系統管理者
    單位
    泌尿部
    建立
    2016-05-10 12:23:00
    最近修訂
    2017-05-09 10:00:23
    長度
    13:41