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00:00
1.
How Low Should Serum Testosterone Level Be in the Treatment of Metastatic Prostate Cancer
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00:19
2.
Therapy-induced HeterogeneityThe Androgen-receptor (AR) Pathway
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01:19
3.
Castration-Resistant Prostate Cancer (CRPC): Definition
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01:56
4.
Testosterone Characteristics
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02:52
5.
Methods for Serum Testosterone Measurement
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03:39
6.
Typical Serum Testosterone Values arePresented in Different Units
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05:50
7.
Management of CRPC: Maintenance of Castrate Testosterone Levels
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07:30
8.
Testosterone levels during ADT may Serve as anEarly Predictor of Prostate Cancer Progression
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08:45
9.
Testosterone Levels during ADT may Predict Risk of Disease Progression
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09:05
10.
Survival Free of AIP According to Serum Testosterone Level
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09:29
11.
Sustained Profound Suppression of Testosterone May Affect Prognosis and Survival
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09:53
12.
The Cumulative Side Effects ofAndrogen Deprivation Syndrome
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10:38
13.
Long-term Side Effects of ADT
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10:49
14.
Rationale of Intermittent Androgen Deprivation (IAD)
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11:55
15.
ADT in Advanced Prostate Cancer:Is IAD the New Standard of Care?
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13:39
16.
Intermittent versus Continuous Androgen Deprivation in Metastatic Hormone Sensitive Prostate Cancer
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14:53
17.
Slide 17
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15:31
18.
Low Nadir Serum Testosterone (<20 ng/dL) within the first year of ADT Predicts Treatment Outcomes
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16:18
19.
Clinical Implication for Patients on Androgen Deprivation Therapy
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17:43
20.
Bipolar Androgen Therapy (BAT): Adaptive auto-regulation of AR and induction of DNA damage with testosterone therapy
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19:34
21.
Slide 21
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21:46
22.
Thank You for Your Attentions